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Flotillin proteins recruit sphingosine to membranes and maintain cellular sphingosine-1-phosphate levels
Sphingosine-1-phosphate (S1P) is an important lipid signalling molecule. S1P is produced via intracellular phosphorylation of sphingosine (Sph). As a lipid with a single fatty alkyl chain, Sph may diffuse rapidly between cellular membranes and through the aqueous phase. Here, we show that the absenc...
Autores principales: | Riento, Kirsi, Zhang, Qifeng, Clark, Jonathan, Begum, Farida, Stephens, Elaine, Wakelam, Michael J., Nichols, Benjamin J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5963794/ https://www.ncbi.nlm.nih.gov/pubmed/29787576 http://dx.doi.org/10.1371/journal.pone.0197401 |
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