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Atypical pharmacology of schistosome TRPA1-like ion channels

Parasitic flatworms of the genus Schistosoma cause schistosomiasis, a neglected tropical disease estimated to affect over 200 million people worldwide. Praziquantel is the only antischistosomal currently available for treatment, and there is an urgent need for new therapeutics. Ion channels play key...

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Detalles Bibliográficos
Autores principales: Bais, Swarna, Berry, Corbett T., Liu, Xiaohong, Ruthel, Gordon, Freedman, Bruce D., Greenberg, Robert M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5963811/
https://www.ncbi.nlm.nih.gov/pubmed/29746471
http://dx.doi.org/10.1371/journal.pntd.0006495