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Metabolic reprogramming of Kaposi’s sarcoma associated herpes virus infected B-cells in hypoxia

Kaposi’s sarcoma associated herpesvirus (KSHV) infection stabilizes hypoxia inducible factors (HIFs). The interaction between KSHV encoded factors and HIFs plays a critical role in KSHV latency, reactivation and associated disease phenotypes. Besides modulation of large-scale signaling, KSHV infecti...

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Detalles Bibliográficos
Autores principales: Singh, Rajnish Kumar, Lang, Fengchao, Pei, Yonggang, Jha, Hem Chandra, Robertson, Erle S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5963815/
https://www.ncbi.nlm.nih.gov/pubmed/29746587
http://dx.doi.org/10.1371/journal.ppat.1007062