Neurochondrin interacts with the SMN protein suggesting a novel mechanism for spinal muscular atrophy pathology

Spinal muscular atrophy (SMA) is an inherited neurodegenerative condition caused by a reduction in the amount of functional survival motor neuron (SMN) protein. SMN has been implicated in transport of mRNA in neural cells for local translation. We previously identified microtubule-dependent mobile v...

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Detalles Bibliográficos
Autores principales: Thompson, Luke W., Morrison, Kim D., Shirran, Sally L., Groen, Ewout J. N., Gillingwater, Thomas H., Botting, Catherine H., Sleeman, Judith E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5963842/
https://www.ncbi.nlm.nih.gov/pubmed/29507115
http://dx.doi.org/10.1242/jcs.211482

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5963842/
https://www.ncbi.nlm.nih.gov/pubmed/29507115
http://dx.doi.org/10.1242/jcs.211482

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