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Mitotic spindle assembly and γ-tubulin localisation depend on the integral nuclear membrane protein Samp1

We have investigated a possible role for the inner nuclear membrane protein Samp1 (also known as TMEM201) in the mitotic machinery. Live-cell imaging showed that Samp1a–YFP (Samp1a is the short isoform of Samp1) distributed as filamentous structures in the mitotic spindle, partially colocalising wit...

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Detalles Bibliográficos
Autores principales: Larsson, Veronica J., Jafferali, Mohammed Hakim, Vijayaraghavan, Balaje, Figueroa, Ricardo A., Hallberg, Einar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5963844/
https://www.ncbi.nlm.nih.gov/pubmed/29514856
http://dx.doi.org/10.1242/jcs.211664