Cargando…

A peek into cancer-associated fibroblasts: origins, functions and translational impact

In malignant tumors, cancer cells adapt to grow within their host tissue. As a cancer progresses, an accompanying host stromal response evolves within and around the nascent tumor. Among the host stromal constituents associated with the tumor are cancer-associated fibroblasts, a highly abundant and...

Descripción completa

Detalles Bibliográficos
Autores principales: LeBleu, Valerie S., Kalluri, Raghu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5963854/
https://www.ncbi.nlm.nih.gov/pubmed/29686035
http://dx.doi.org/10.1242/dmm.029447