Regulation and function of H3K36 di-methylation by the trithorax-group protein complex AMC

The Drosophila Ash1 protein is a trithorax-group (trxG) regulator that antagonizes Polycomb repression at HOX genes. Ash1 di-methylates lysine 36 in histone H3 (H3K36me2) but how this activity is controlled and at which genes it functions is not well understood. We show that Ash1 protein purified fr...

Descripción completa

Detalles Bibliográficos
Autores principales: Schmähling, Sigrun, Meiler, Arno, Lee, Yoonjung, Mohammed, Arif, Finkl, Katja, Tauscher, Katharina, Israel, Lars, Wirth, Marc, Philippou-Massier, Julia, Blum, Helmut, Habermann, Bianca, Imhof, Axel, Song, Ji-Joon, Müller, Jürg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5963871/
https://www.ncbi.nlm.nih.gov/pubmed/29540501
http://dx.doi.org/10.1242/dev.163808

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5963871/
https://www.ncbi.nlm.nih.gov/pubmed/29540501
http://dx.doi.org/10.1242/dev.163808

Ejemplares similares