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Lack of Tumorigenicity of Aminopyrine Orally Administered to B6C3F(1) Mice

To test the tumorigenic potential of aminopyrine, an antipyretic analgesic, it was administered in drinking water at levels of 0 (control), 0.04 and 0.08% to 50 male and 50 female B6C3F(1), mice for 100 weeks, and the mice were subsequently maintained without aminopyrine for a further 4 weeks. The m...

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Detalles Bibliográficos
Autores principales: Inai, Kouki, Kobuke, Toshihiro, Fujihara, Megumu, Yonehara, Shuji, Takemoto, Tsuyoshi, Tsuya, Takafumi, Yamamoto, Atsushi, Tachiyama, Yoshiro, Izumi, Kumiko, Tokuoka, Shoji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1990
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5963906/
https://www.ncbi.nlm.nih.gov/pubmed/2110128
http://dx.doi.org/10.1111/j.1349-7006.1990.tb02537.x