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A window into extreme longevity; the circulating metabolomic signature of the naked mole-rat, a mammal that shows negligible senescence

Mouse-sized naked mole-rats (Heterocephalus glaber), unlike other mammals, do not conform to Gompertzian laws of age-related mortality; adults show no age-related change in mortality risk. Moreover, we observe negligible hallmarks of aging with well-maintained physiological and molecular functions,...

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Detalles Bibliográficos
Autores principales: Lewis, Kaitlyn N., Rubinstein, Nimrod D., Buffenstein, Rochelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964061/
https://www.ncbi.nlm.nih.gov/pubmed/29679203
http://dx.doi.org/10.1007/s11357-018-0014-2