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A window into extreme longevity; the circulating metabolomic signature of the naked mole-rat, a mammal that shows negligible senescence
Mouse-sized naked mole-rats (Heterocephalus glaber), unlike other mammals, do not conform to Gompertzian laws of age-related mortality; adults show no age-related change in mortality risk. Moreover, we observe negligible hallmarks of aging with well-maintained physiological and molecular functions,...
Autores principales: | Lewis, Kaitlyn N., Rubinstein, Nimrod D., Buffenstein, Rochelle |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964061/ https://www.ncbi.nlm.nih.gov/pubmed/29679203 http://dx.doi.org/10.1007/s11357-018-0014-2 |
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