The Effects of Anti-LAP Monoclonal Antibody Down-regulation of CD4+LAP+ T Cells on Allogeneic Corneal Transplantation in Mice

CD4+latency-associated peptide (LAP)+ T cells are a newly discovered T cell subset with suppressive function on immune responses. In this study, we investigate the role of CD4+LAP+ T cells on mice corneal allograft survival by down-regulating their expression using anti-LAP mAb. We show that a block...

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Detalles Bibliográficos
Autores principales: Li, Shang, Lu, Hongshuang, Sella, Ruti, Zhang, Wei, Dong, Hongwei, Guo, Chungang, Afshari, Natalie A., Pan, Zhiqiang, Jie, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964070/
https://www.ncbi.nlm.nih.gov/pubmed/29789580
http://dx.doi.org/10.1038/s41598-018-26235-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964070/
https://www.ncbi.nlm.nih.gov/pubmed/29789580
http://dx.doi.org/10.1038/s41598-018-26235-5

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