Triad3a induces the degradation of early necrosome to limit RipK1-dependent cytokine production and necroptosis

Understanding the molecular signaling in programmed cell death is vital to a practical understanding of inflammation and immune cell function. Here we identify a previously unrecognized mechanism that functions to downregulate the necrosome, a central signaling complex involved in inflammation and n...

Descripción completa

Detalles Bibliográficos
Autores principales: Alturki, Norah A., McComb, Scott, Ariana, Ardeshir, Rijal, Dikchha, Korneluk, Robert G., Sun, Shao-Cong, Alnemri, Emad, Sad, Subash
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964080/
https://www.ncbi.nlm.nih.gov/pubmed/29789521
http://dx.doi.org/10.1038/s41419-018-0672-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964080/
https://www.ncbi.nlm.nih.gov/pubmed/29789521
http://dx.doi.org/10.1038/s41419-018-0672-0

Ejemplares similares