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Triad3a induces the degradation of early necrosome to limit RipK1-dependent cytokine production and necroptosis
Understanding the molecular signaling in programmed cell death is vital to a practical understanding of inflammation and immune cell function. Here we identify a previously unrecognized mechanism that functions to downregulate the necrosome, a central signaling complex involved in inflammation and n...
Autores principales: | Alturki, Norah A., McComb, Scott, Ariana, Ardeshir, Rijal, Dikchha, Korneluk, Robert G., Sun, Shao-Cong, Alnemri, Emad, Sad, Subash |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964080/ https://www.ncbi.nlm.nih.gov/pubmed/29789521 http://dx.doi.org/10.1038/s41419-018-0672-0 |
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