Regulator of chromatin condensation 1 abrogates the G1 cell cycle checkpoint via Cdk1 in human papillomavirus E7-expressing epithelium and cervical cancer cells

Regulator of chromatin condensation 1 (RCC1) is a major guanine-nucleotide exchange factor for Ran GTPase and plays key roles in nucleo-cytoplasmic transport, mitosis, and nuclear envelope assembly. RCC1 is known to be a critical cell cycle regulator whose loss causes G1 phase arrest, but the molecu...

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Detalles Bibliográficos
Autores principales: Qiao, Lijun, Zheng, Jingyi, Tian, Yonghao, Zhang, Qishu, Wang, Xiao, Chen, Jason J., Zhang, Weifang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964113/
https://www.ncbi.nlm.nih.gov/pubmed/29789527
http://dx.doi.org/10.1038/s41419-018-0584-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964113/
https://www.ncbi.nlm.nih.gov/pubmed/29789527
http://dx.doi.org/10.1038/s41419-018-0584-z

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