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Regulator of chromatin condensation 1 abrogates the G1 cell cycle checkpoint via Cdk1 in human papillomavirus E7-expressing epithelium and cervical cancer cells
Regulator of chromatin condensation 1 (RCC1) is a major guanine-nucleotide exchange factor for Ran GTPase and plays key roles in nucleo-cytoplasmic transport, mitosis, and nuclear envelope assembly. RCC1 is known to be a critical cell cycle regulator whose loss causes G1 phase arrest, but the molecu...
Autores principales: | Qiao, Lijun, Zheng, Jingyi, Tian, Yonghao, Zhang, Qishu, Wang, Xiao, Chen, Jason J., Zhang, Weifang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964113/ https://www.ncbi.nlm.nih.gov/pubmed/29789527 http://dx.doi.org/10.1038/s41419-018-0584-z |
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