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Metabolic Reprogramming in Modulating T Cell Reactive Oxygen Species Generation and Antioxidant Capacity

A robust adaptive immune response requires a phase of proliferative burst which is followed by the polarization of T cells into relevant functional subsets. Both processes are associated with dramatically increased bioenergetics demands, biosynthetic demands, and redox demands. T cells meet these de...

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Detalles Bibliográficos
Autores principales: Rashida Gnanaprakasam, Josephin N., Wu, Ruohan, Wang, Ruoning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964129/
https://www.ncbi.nlm.nih.gov/pubmed/29868027
http://dx.doi.org/10.3389/fimmu.2018.01075