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Parathyroid Hormone-Related Protein Negatively Regulates Tumor Cell Dormancy Genes in a PTHR1/Cyclic AMP-Independent Manner

Parathyroid hormone-related protein (PTHrP) expression in breast cancer is enriched in bone metastases compared to primary tumors. Human MCF7 breast cancer cells “home” to the bones of immune deficient mice following intracardiac inoculation, but do not grow well and stain negatively for Ki67, thus...

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Detalles Bibliográficos
Autores principales: Johnson, Rachelle W., Sun, Yao, Ho, Patricia W. M., Chan, Audrey S. M., Johnson, Jasmine A., Pavlos, Nathan J., Sims, Natalie A., Martin, T. John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964132/
https://www.ncbi.nlm.nih.gov/pubmed/29867773
http://dx.doi.org/10.3389/fendo.2018.00241