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HMGA1 exacerbates tumor growth through regulating the cell cycle and accelerates migration/invasion via targeting miR-221/222 in cervical cancer

High-mobility group AT-hook1 (HMGA1, formerly HMG-I/Y), an architectural transcription factor, participates in a number of tumor biological processes. However, its effect on cervical cancer remains largely indistinct. In this study, we found that HMGA1 was generally overexpressed in cervical cancer...

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Detalles Bibliográficos
Autores principales: Fu, Fangfang, Wang, Tian, Wu, Zhangying, Feng, Yourong, Wang, Wenwen, Zhou, Su, Ma, Xiangyi, Wang, Shixuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964147/
https://www.ncbi.nlm.nih.gov/pubmed/29789601
http://dx.doi.org/10.1038/s41419-018-0683-x