SK channel activation is neuroprotective in conditions of enhanced ER–mitochondrial coupling

Alterations in the strength and interface area of contact sites between the endoplasmic reticulum (ER) and mitochondria contribute to calcium (Ca(2+)) dysregulation and neuronal cell death, and have been implicated in the pathology of several neurodegenerative diseases. Weakening this physical linka...

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Detalles Bibliográficos
Autores principales: Honrath, Birgit, Krabbendam, Inge E., IJsebaart, Carmen, Pegoretti, Valentina, Bendridi, Nadia, Rieusset, Jennifer, Schmidt, Martina, Culmsee, Carsten, Dolga, Amalia M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964177/
https://www.ncbi.nlm.nih.gov/pubmed/29789578
http://dx.doi.org/10.1038/s41419-018-0590-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964177/
https://www.ncbi.nlm.nih.gov/pubmed/29789578
http://dx.doi.org/10.1038/s41419-018-0590-1

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