Cargando…

SK channel activation is neuroprotective in conditions of enhanced ER–mitochondrial coupling

Alterations in the strength and interface area of contact sites between the endoplasmic reticulum (ER) and mitochondria contribute to calcium (Ca(2+)) dysregulation and neuronal cell death, and have been implicated in the pathology of several neurodegenerative diseases. Weakening this physical linka...

Descripción completa

Detalles Bibliográficos
Autores principales:	Honrath, Birgit, Krabbendam, Inge E., IJsebaart, Carmen, Pegoretti, Valentina, Bendridi, Nadia, Rieusset, Jennifer, Schmidt, Martina, Culmsee, Carsten, Dolga, Amalia M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964177/ https://www.ncbi.nlm.nih.gov/pubmed/29789578 http://dx.doi.org/10.1038/s41419-018-0590-1

Ejemplares similares

Glucose-regulated protein 75 determines ER–mitochondrial coupling and sensitivity to oxidative stress in neuronal cells
por: Honrath, Birgit, et al.
Publicado: (2017)

Protective Roles for Potassium SK/K(Ca)2 Channels in Microglia and Neurons
por: Dolga, Amalia M., et al.
Publicado: (2012)

SK-Channel Activation Alters Peripheral Metabolic Pathways in Mice, but Not Lipopolysaccharide-Induced Fever or Inflammation
por: Bredehöft, Janne, et al.
Publicado: (2022)

One protein, different cell fate: the differential outcome of depleting GRP75 during oxidative stress in neurons
por: Honrath, Birgit, et al.
Publicado: (2018)

SK channel-mediated metabolic escape to glycolysis inhibits ferroptosis and supports stress resistance in C. elegans
por: Krabbendam, Inge E., et al.
Publicado: (2020)

Subcellular expression and neuroprotective effects of SK channels in human dopaminergic neurons
por: Dolga, A M, et al.
Publicado: (2014)

The neuroprotective role of microglial cells against amyloid beta‐mediated toxicity in organotypic hippocampal slice cultures
por: Richter, Maren, et al.
Publicado: (2020)

Inhibition of HIF-prolyl-4-hydroxylases prevents mitochondrial impairment and cell death in a model of neuronal oxytosis
por: Neitemeier, S, et al.
Publicado: (2016)

Calcium channel ITPR2 and mitochondria–ER contacts promote cellular senescence and aging
por: Ziegler, Dorian V., et al.
Publicado: (2021)

Coupling of SK channels, L-type Ca(2+) channels, and ryanodine receptors in cardiomyocytes
por: Zhang, Xiao-Dong, et al.
Publicado: (2018)

Hepatitis C virus replication requires integrity of mitochondria-associated ER membranes
por: Duponchel, Sarah, et al.
Publicado: (2022)

Preferential formation of human heteromeric SK2:SK3 channels limits homomeric SK channel assembly and function
por: Butler, Andrew S., et al.
Publicado: (2022)

Cytochrome c Oxidase Inhibition by ATP Decreases Mitochondrial ROS Production
por: Ramzan, Rabia, et al.
Publicado: (2022)

Roles of the Drosophila SK Channel (dSK) in Courtship Memory
por: Abou Tayoun, Ahmad N., et al.
Publicado: (2012)

Enhanced firing of locus coeruleus neurons and SK channel dysfunction are conserved in distinct models of prodromal Parkinson’s disease
por: Matschke, Lina A., et al.
Publicado: (2022)

Age-dependent neuroprotective effect of an SK3 channel agonist on excitotoxity to dopaminergic neurons in organotypic culture
por: Maldonado, Oscar, et al.
Publicado: (2020)

α(1)-antitrypsin modulates microglial-mediated neuroinflammation and protects microglial cells from amyloid-β-induced toxicity
por: Gold, Maike, et al.
Publicado: (2014)

Effect of Metformin on T2D-Induced MAM Ca(2+) Uncoupling and Contractile Dysfunction in an Early Mouse Model of Diabetic HFpEF
por: Dia, Maya, et al.
Publicado: (2022)

Orai1 Boosts SK3 Channel Activation
por: Tiffner, Adéla, et al.
Publicado: (2021)

CRAC and SK Channels: Their Molecular Mechanisms Associated with Cancer Cell Development
por: Tiffner, Adéla, et al.
Publicado: (2022)

The SK2-Long Isoform Directs Synaptic Localization and Function of SK2-containing channels
por: Allen, Duane, et al.
Publicado: (2011)

BID links ferroptosis to mitochondrial cell death pathways
por: Neitemeier, Sandra, et al.
Publicado: (2017)

Lithium protects hippocampal progenitors, cognitive performance and hypothalamus–pituitary function after irradiation to the juvenile rat brain
por: Zhou, Kai, et al.
Publicado: (2017)

Dying transplanted neural stem cells mediate survival bystander effects in the injured brain
por: Han, Wei, et al.
Publicado: (2023)

Correction: Dying transplanted neural stem cells mediate survival bystander effects in the injured brain
por: Han, Wei, et al.
Publicado: (2023)

Enhanced Glucose Tolerance by SK4 Channel Inhibition in Pancreatic β-Cells
por: Düfer, Martina, et al.
Publicado: (2009)

Structural insights into the potency of SK channel positive modulators
por: Nam, Young-Woo, et al.
Publicado: (2017)

EF hands at the N-lobe of calmodulin are required for both SK channel gating and stable SK–calmodulin interaction
por: Li, Weiyan, et al.
Publicado: (2009)

Molecular overlap in the regulation of SK channels by small molecules and phosphoinositides
por: Zhang, Miao, et al.
Publicado: (2015)

Plasma hsa‐mir‐19b is a potential LevoDopa therapy marker
por: Chis, Aimee Rodica, et al.
Publicado: (2021)

Fibril polymorphism affects immobilized non-amyloid flanking domains of huntingtin exon1 rather than its polyglutamine core
por: Lin, Hsiang-Kai, et al.
Publicado: (2017)

Mitochondrial damage by α-synuclein causes cell death in human dopaminergic neurons
por: Ganjam, Goutham K., et al.
Publicado: (2019)

SK4 K(+) channels are therapeutic targets for the treatment of cardiac arrhythmias
por: Haron‐Khun, Shiraz, et al.
Publicado: (2017)

K(Ca)2 and K(Ca)3 Channels in Learning and Memory Processes, and Neurodegeneration
por: Kuiper, Els F. E., et al.
Publicado: (2012)

Interaction of the Psychiatric Risk Gene Cacna1c With Post-weaning Social Isolation or Environmental Enrichment Does Not Affect Brain Mitochondrial Bioenergetics in Rats
por: Michels, Susanne, et al.
Publicado: (2019)

Study of Atmospheric Neutrino Oscillations in SK-I and SK-II
por: Nakayama, S
Publicado: (2005)

Impaired aerobic capacity and premature fatigue preceding muscle weakness in the skeletal muscle Tfam-knockout mouse model
por: Chatel, Benjamin, et al.
Publicado: (2021)

Paradoxical Contribution of SK3 and GIRK Channels to the Activation of Mouse Vomeronasal Organ
por: Kim, SangSeong, et al.
Publicado: (2012)

Modulating fear extinction memory by manipulating SK potassium channels in the infralimbic cortex
por: Criado-Marrero, Marangelie, et al.
Publicado: (2014)

Control of Ca(2+) Influx and Calmodulin Activation by SK-Channels in Dendritic Spines
por: Griffith, Thom, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_dpto4u28cmrn8irmhl32eb238o