Alterations in serum kynurenine pathway metabolites in individuals with high neocortical amyloid-β load: A pilot study

The kynurenine pathway (KP) is dysregulated in neuroinflammatory diseases including Alzheimer’s disease (AD), however has not been investigated in preclinical AD characterized by high neocortical amyloid-β load (NAL), prior to cognitive impairment. Serum KP metabolites were measured in the cognitive...

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Detalles Bibliográficos
Autores principales: Chatterjee, Pratishtha, Goozee, Kathryn, Lim, Chai K., James, Ian, Shen, Kaikai, Jacobs, Kelly R., Sohrabi, Hamid R., Shah, Tejal, Asih, Prita R., Dave, Preeti, ManYan, Candice, Taddei, Kevin, Lovejoy, David B., Chung, Roger, Guillemin, Gilles J., Martins, Ralph N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964182/
https://www.ncbi.nlm.nih.gov/pubmed/29789640
http://dx.doi.org/10.1038/s41598-018-25968-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964182/
https://www.ncbi.nlm.nih.gov/pubmed/29789640
http://dx.doi.org/10.1038/s41598-018-25968-7

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