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Autophagy Disruptions Associated With Altered Optineurin Expression in Extranigral Regions in a Rotenone Model of Parkinson's Disease

The motor features of Parkinson's disease (PD) primarily result from a lesion to the nigrostriatal dopamine system. Numerous non-motor symptoms occur in PD, many of which are postulated to stem from pathology outside of the nigrostriatal dopamine system. Perturbations to protein trafficking, di...

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Detalles Bibliográficos
Autores principales: Wise, John P., Price, Charles G., Amaro, Joseph A., Cannon, Jason R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964216/
https://www.ncbi.nlm.nih.gov/pubmed/29867311
http://dx.doi.org/10.3389/fnins.2018.00289