A20 critically controls microglia activation and inhibits inflammasome-dependent neuroinflammation

Microglia, the mononuclear phagocytes of the central nervous system (CNS), are important for the maintenance of CNS homeostasis, but also critically contribute to CNS pathology. Here we demonstrate that the nuclear factor kappa B (NF-κB) regulatory protein A20 is crucial in regulating microglia acti...

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Detalles Bibliográficos
Autores principales: Voet, Sofie, Mc Guire, Conor, Hagemeyer, Nora, Martens, Arne, Schroeder, Anna, Wieghofer, Peter, Daems, Carmen, Staszewski, Ori, Vande Walle, Lieselotte, Jordao, Marta Joana Costa, Sze, Mozes, Vikkula, Hanna-Kaisa, Demeestere, Delphine, Van Imschoot, Griet, Scott, Charlotte L., Hoste, Esther, Gonçalves, Amanda, Guilliams, Martin, Lippens, Saskia, Libert, Claude, Vandenbroucke, Roos E., Kim, Ki-Wook, Jung, Steffen, Callaerts-Vegh, Zsuzsanna, Callaerts, Patrick, de Wit, Joris, Lamkanfi, Mohamed, Prinz, Marco, van Loo, Geert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964249/
https://www.ncbi.nlm.nih.gov/pubmed/29789522
http://dx.doi.org/10.1038/s41467-018-04376-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964249/
https://www.ncbi.nlm.nih.gov/pubmed/29789522
http://dx.doi.org/10.1038/s41467-018-04376-5

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