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The Major Role of NF-κB in the Depth of Invasion on Acral Melanoma by Decreasing CD8(+) T Cells

BACKGROUND: The tumor microenvironment including immune surveillance affects malignant melanoma (MM) behavior. Nuclear factor κB (NF-κB) stimulates the transcription of various genes in the nucleus and plays a role in the inflammatory process and in tumorigenesis. CD8(+) T cells have cytotoxic prope...

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Detalles Bibliográficos
Autores principales: Usman, Hermin Aminah, Hernowo, Bethy S., Tobing, Maringan Diapari Lumban, Hindritiani, Reti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Pathologists and the Korean Society for Cytopathology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964292/
https://www.ncbi.nlm.nih.gov/pubmed/29673240
http://dx.doi.org/10.4132/jptm.2018.04.04