Stimulator of Interferon Genes in Classical Dendritic Cells Controls Mucosal Th17 Responses to Cyclic Dinucleotides for Host Defenses Against Microbial Infections in Gut

Cyclic dinucleotides are bacterial signal transducers that bind to host intracellular protein, stimulator of interferon genes (STING) encoded by Tmem173. In this study, we demonstrate that STING triggers adaptive immune responses that control Th17 differentiation. Cyclic dinucleotides recognition en...

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Detalles Bibliográficos
Autores principales: Liu, Song, Xia, Qiuyuan, Wu, Xiuwen, Sun, Feng, Hu, Qiongyuan, Wu, Jie, Wang, Meng, Rao, Qiu, Guan, Wenxian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964311/
https://www.ncbi.nlm.nih.gov/pubmed/29868030
http://dx.doi.org/10.3389/fimmu.2018.01085

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964311/
https://www.ncbi.nlm.nih.gov/pubmed/29868030
http://dx.doi.org/10.3389/fimmu.2018.01085

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