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Stimulator of Interferon Genes in Classical Dendritic Cells Controls Mucosal Th17 Responses to Cyclic Dinucleotides for Host Defenses Against Microbial Infections in Gut
Cyclic dinucleotides are bacterial signal transducers that bind to host intracellular protein, stimulator of interferon genes (STING) encoded by Tmem173. In this study, we demonstrate that STING triggers adaptive immune responses that control Th17 differentiation. Cyclic dinucleotides recognition en...
Autores principales: | Liu, Song, Xia, Qiuyuan, Wu, Xiuwen, Sun, Feng, Hu, Qiongyuan, Wu, Jie, Wang, Meng, Rao, Qiu, Guan, Wenxian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964311/ https://www.ncbi.nlm.nih.gov/pubmed/29868030 http://dx.doi.org/10.3389/fimmu.2018.01085 |
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