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The CPLANE protein Intu protects kidneys from ischemia-reperfusion injury by targeting STAT1 for degradation

Intu is known as a ciliogenesis and planar polarity effector (CPLANE) protein. Although roles for Intu have been reported during embryonic development and in the context of developmental disorders, its function and regulation in adult tissues remain poorly understood. Here we show that ablation of I...

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Detalles Bibliográficos
Autores principales: Wang, Shixuan, Liu, Aimin, Wu, Guangyu, Ding, Han-Fei, Huang, Shuang, Nahman, Stanley, Dong, Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964315/
https://www.ncbi.nlm.nih.gov/pubmed/29581513
http://dx.doi.org/10.1038/s41467-018-03628-8