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The CPLANE protein Intu protects kidneys from ischemia-reperfusion injury by targeting STAT1 for degradation
Intu is known as a ciliogenesis and planar polarity effector (CPLANE) protein. Although roles for Intu have been reported during embryonic development and in the context of developmental disorders, its function and regulation in adult tissues remain poorly understood. Here we show that ablation of I...
Autores principales: | Wang, Shixuan, Liu, Aimin, Wu, Guangyu, Ding, Han-Fei, Huang, Shuang, Nahman, Stanley, Dong, Zheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964315/ https://www.ncbi.nlm.nih.gov/pubmed/29581513 http://dx.doi.org/10.1038/s41467-018-03628-8 |
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