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The RNA-binding protein ARPP21 controls dendritic branching by functionally opposing the miRNA it hosts

About half of mammalian miRNA genes lie within introns of protein-coding genes, yet little is known about functional interactions between miRNAs and their host genes. The intronic miRNA miR-128 regulates neuronal excitability and dendritic morphology of principal neurons during mouse cerebral cortex...

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Detalles Bibliográficos
Autores principales: Rehfeld, Frederick, Maticzka, Daniel, Grosser, Sabine, Knauff, Pina, Eravci, Murat, Vida, Imre, Backofen, Rolf, Wulczyn, F. Gregory
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964322/
https://www.ncbi.nlm.nih.gov/pubmed/29581509
http://dx.doi.org/10.1038/s41467-018-03681-3