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Role of Severe Acute Respiratory Syndrome Coronavirus Viroporins E, 3a, and 8a in Replication and Pathogenesis

Viroporins are viral proteins with ion channel (IC) activity that play an important role in several processes, including virus replication and pathogenesis. While many coronaviruses (CoVs) encode two viroporins, severe acute respiratory syndrome CoV (SARS-CoV) encodes three: proteins 3a, E, and 8a....

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Detalles Bibliográficos
Autores principales: Castaño-Rodriguez, Carlos, Honrubia, Jose M., Gutiérrez-Álvarez, Javier, DeDiego, Marta L., Nieto-Torres, Jose L., Jimenez-Guardeño, Jose M., Regla-Nava, Jose A., Fernandez-Delgado, Raul, Verdia-Báguena, Carmina, Queralt-Martín, Maria, Kochan, Grazyna, Perlman, Stanley, Aguilella, Vicente M., Sola, Isabel, Enjuanes, Luis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964350/
https://www.ncbi.nlm.nih.gov/pubmed/29789363
http://dx.doi.org/10.1128/mBio.02325-17