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Myoblast Myogenic Differentiation but Not Fusion Process Is Inhibited via MyoD Tetraplex Interaction

The presence of tetraplex structures in the promoter region of the myogenic differentiation 1 gene (MyoD1) was investigated with a specific tetraplex-binding porphyrin (TMPyP4), to test its influence on the expression of MyoD1 itself and downstream-regulated genes during myogenic differentiation. TM...

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Detalles Bibliográficos
Autores principales: Testa, Stefano, D'Addabbo, Pietro, Fornetti, Ersilia, Belli, Roberta, Fuoco, Claudia, Bernardini, Sergio, Cannata, Stefano, Frezza, Domenico, Gargioli, Cesare
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964432/
https://www.ncbi.nlm.nih.gov/pubmed/29854094
http://dx.doi.org/10.1155/2018/7640272