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Senescence drives non-cell autonomous tumorigenesis in the pituitary gland

Novel detrimental functions of senescent cells have been recently uncovered in the context of cancer development and progression, which they mainly exert through the secretion of several pro-tumorigenic factors. Here we discuss how cellular senescence and its secretory phenotype can be involved in t...

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Detalles Bibliográficos
Autores principales: Gonzalez-Meljem, Jose Mario, Martinez-Barbera, Juan Pedro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964449/
https://www.ncbi.nlm.nih.gov/pubmed/29876518
http://dx.doi.org/10.1080/23723556.2018.1435180