Linking PRMT5 to breast cancer stem cells: New therapeutic opportunities?

The arginine methyltransferase PRMT5 has been increasingly associated with cancer development. Here we describe our recent findings that PRMT5 is a critical regulator of breast cancer stem cell survival via the epigenetic regulation of FOXP1. Consequently, PRMT5 inhibitors could potentially eradicat...

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Detalles Bibliográficos
Autores principales: Chiang, Kelly, Davies, Clare C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964458/
https://www.ncbi.nlm.nih.gov/pubmed/29876520
http://dx.doi.org/10.1080/23723556.2018.1441628

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964458/
https://www.ncbi.nlm.nih.gov/pubmed/29876520
http://dx.doi.org/10.1080/23723556.2018.1441628

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