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The antifungal Aureobasidin A and an analogue are active against the protozoan parasite Toxoplasma gondii but do not inhibit sphingolipid biosynthesis

Toxoplasma gondii is an obligate intracellular protozoan parasite of the phylum Apicomplexa, and toxoplasmosis is an important disease of both humans and economically important animals. With a limited array of drugs available there is a need to identify new therapeutic compounds. Aureobasidin A (AbA...

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Detalles Bibliográficos
Autores principales: ALQAISI, A. Q. I., MBEKEANI, A. J., LLORENS, M. BASSAS, ELHAMMER, A. P., DENNY, P. W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964465/
https://www.ncbi.nlm.nih.gov/pubmed/28486997
http://dx.doi.org/10.1017/S0031182017000506