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Everybody needs sphingolipids, right! Mining for new drug targets in protozoan sphingolipid biosynthesis

Sphingolipids (SLs) are an integral part of all eukaryotic cellular membranes. In addition, they have indispensable functions as signalling molecules controlling a myriad of cellular events. Disruption of either the de novo synthesis or the degradation pathways has been shown to have detrimental eff...

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Detalles Bibliográficos
Autores principales: MINA, JOHN G. M., DENNY, P. W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964470/
https://www.ncbi.nlm.nih.gov/pubmed/28637533
http://dx.doi.org/10.1017/S0031182017001081