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Everybody needs sphingolipids, right! Mining for new drug targets in protozoan sphingolipid biosynthesis
Sphingolipids (SLs) are an integral part of all eukaryotic cellular membranes. In addition, they have indispensable functions as signalling molecules controlling a myriad of cellular events. Disruption of either the de novo synthesis or the degradation pathways has been shown to have detrimental eff...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cambridge University Press
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964470/ https://www.ncbi.nlm.nih.gov/pubmed/28637533 http://dx.doi.org/10.1017/S0031182017001081 |