Cysteamine, an Endogenous Aminothiol, and Cystamine, the Disulfide Product of Oxidation, Increase Pseudomonas aeruginosa Sensitivity to Reactive Oxygen and Nitrogen Species and Potentiate Therapeutic Antibiotics against Bacterial Infection

Cysteamine is an endogenous aminothiol produced in mammalian cells as a consequence of coenzyme A metabolism through the activity of the vanin family of pantetheinase ectoenzymes. It is known to have a biological role in oxidative stress, inflammation, and cell migration. There have been several rep...

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Detalles Bibliográficos
Autores principales: Fraser-Pitt, Douglas J., Mercer, Derry K., Smith, Daniel, Kowalczuk, Aleksandra, Robertson, Jennifer, Lovie, Emma, Perenyi, Peter, Cole, Michelle, Doumith, Michel, Hill, Robert L. R., Hopkins, Katie L., Woodford, Neil, O'Neil, Deborah A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Bacterial Infections
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964511/
https://www.ncbi.nlm.nih.gov/pubmed/29581193
http://dx.doi.org/10.1128/IAI.00947-17

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964511/
https://www.ncbi.nlm.nih.gov/pubmed/29581193
http://dx.doi.org/10.1128/IAI.00947-17

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