Sister Chromatid Exchange and Genomic Instability in Soft Tissue Sarcomas: Potential Implications for Response to DNA-Damaging Treatments

Sarcomas are rare heterogeneous malignancies of mesenchymal origin characterised by complex karyotypes but no specific abnormalities. Recurrence is common, and metastatic disease carries poor survival despite standard DNA-damaging radiotherapy or chemotherapy. DNA double-strand breaks (DSBs) are eit...

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Detalles Bibliográficos
Autores principales: Salawu, Abdulazeez, Wright, Kristin, Al-Kathiri, Afnan, Wyld, Lynda, Reed, Malcolm, Sisley, Karen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964616/
https://www.ncbi.nlm.nih.gov/pubmed/29853780
http://dx.doi.org/10.1155/2018/3082526

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964616/
https://www.ncbi.nlm.nih.gov/pubmed/29853780
http://dx.doi.org/10.1155/2018/3082526

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