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Sister Chromatid Exchange and Genomic Instability in Soft Tissue Sarcomas: Potential Implications for Response to DNA-Damaging Treatments

Sarcomas are rare heterogeneous malignancies of mesenchymal origin characterised by complex karyotypes but no specific abnormalities. Recurrence is common, and metastatic disease carries poor survival despite standard DNA-damaging radiotherapy or chemotherapy. DNA double-strand breaks (DSBs) are eit...

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Detalles Bibliográficos
Autores principales:	Salawu, Abdulazeez, Wright, Kristin, Al-Kathiri, Afnan, Wyld, Lynda, Reed, Malcolm, Sisley, Karen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964616/ https://www.ncbi.nlm.nih.gov/pubmed/29853780 http://dx.doi.org/10.1155/2018/3082526

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