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Control of the proportion of inner cells by asymmetric divisions and the ensuing resilience of cloned rabbit embryos

Mammalian embryo cloning by nuclear transfer has a low success rate. This is hypothesized to correlate with a high variability of early developmental steps that segregate outer cells, which are fated to extra-embryonic tissues, from inner cells, which give rise to the embryo proper. Exploring the ce...

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Detalles Bibliográficos
Autores principales: Fabrèges, Dimitri, Daniel, Nathalie, Duranthon, Véronique, Peyriéras, Nadine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964649/
https://www.ncbi.nlm.nih.gov/pubmed/29567671
http://dx.doi.org/10.1242/dev.152041