T cells with low CD2 levels express reduced restriction factors and are preferentially infected in therapy naïve chronic HIV-1 patients

Introduction: Restriction factors (RFs) suppress HIV-1 in cell lines and primary cell models. Hence, RFs might be attractive targets for novel antiviral strategies, but their importance for virus control in vivo is controversial. Methods: We profiled the expression of RFs in primary blood-derived mo...

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Detalles Bibliográficos
Autores principales: Bolduan, Sebastian, Koppensteiner, Herwig, Businger, Ramona, Rebensburg, Stephanie, Kunze, Christine, Brack-Werner, Ruth, Draenert, Rika, Schindler, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964667/
https://www.ncbi.nlm.nih.gov/pubmed/28953327
http://dx.doi.org/10.7448/IAS.20.1.21865

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964667/
https://www.ncbi.nlm.nih.gov/pubmed/28953327
http://dx.doi.org/10.7448/IAS.20.1.21865

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