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Epigenetic aging of human hematopoietic cells is not accelerated upon transplantation into mice
BACKGROUND: Transplantation of human hematopoietic stem cells into immunodeficient mice provides a powerful in vivo model system to gain functional insights into hematopoietic differentiation. So far, it remains unclear if epigenetic changes of normal human hematopoiesis are recapitulated upon engra...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964682/ https://www.ncbi.nlm.nih.gov/pubmed/29796118 http://dx.doi.org/10.1186/s13148-018-0499-7 |