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Epigenetic aging of human hematopoietic cells is not accelerated upon transplantation into mice

BACKGROUND: Transplantation of human hematopoietic stem cells into immunodeficient mice provides a powerful in vivo model system to gain functional insights into hematopoietic differentiation. So far, it remains unclear if epigenetic changes of normal human hematopoiesis are recapitulated upon engra...

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Detalles Bibliográficos
Autores principales:	Frobel, Joana, Rahmig, Susann, Franzen, Julia, Waskow, Claudia, Wagner, Wolfgang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Short Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964682/ https://www.ncbi.nlm.nih.gov/pubmed/29796118 http://dx.doi.org/10.1186/s13148-018-0499-7

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