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Novel TNF receptor-1 inhibitors identified as potential therapeutic candidates for traumatic brain injury

BACKGROUND: Traumatic brain injury (TBI) begins with the application of mechanical force to the head or brain, which initiates systemic and cellular processes that are hallmarks of the disease. The pathological cascade of secondary injury processes, including inflammation, can exacerbate brain injur...

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Detalles Bibliográficos
Autores principales: Rowe, Rachel K., Harrison, Jordan L., Zhang, Hongtao, Bachstetter, Adam D., Hesson, David P., O’Hara, Bruce F., Greene, Mark I., Lifshitz, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964690/
https://www.ncbi.nlm.nih.gov/pubmed/29789012
http://dx.doi.org/10.1186/s12974-018-1200-y