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Differential regulation of nimodipine-sensitive and -insensitive Ca(2+) influx by the Na(+)/Ca(2+) exchanger and mitochondria in the rat suprachiasmatic nucleus neurons

BACKGROUND: Transmembrane Ca(2+) influx is critical for molecular rhythmicity, metabolic activity, and neuropeptide release in the central clock of the suprachiasmatic nucleus (SCN). We previously reported that both the Na(+)/Ca(2+) exchanger (NCX) and mitochondria play a role in regulating intracel...

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Detalles Bibliográficos
Autores principales: Cheng, Pi-Cheng, Wang, Yi-Chi, Chen, Ya-Shuan, Cheng, Ruo-Ciao, Yang, Jyh-Jeen, Huang, Rong-Chi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964920/
https://www.ncbi.nlm.nih.gov/pubmed/29788971
http://dx.doi.org/10.1186/s12929-018-0447-z