Ecto-5′-nucleotidase (CD73) attenuates inflammation after spinal cord injury by promoting macrophages/microglia M2 polarization in mice

BACKGROUND: Immune activation, specifically activation of macrophages and resident microglia, leading to inflammation is a key component in the progression of spinal cord injury (SCI). Macrophages/microglia exist in two states—the classically activated M1 phenotype that confers pro-inflammatory effe...

Descripción completa

Detalles Bibliográficos
Autores principales: Xu, Shun, Zhu, Wei, Shao, Minghao, Zhang, Fan, Guo, Ji, Xu, Haocheng, Jiang, Jianyuan, Ma, Xiaosheng, Xia, Xinlei, Zhi, Xiuling, Zhou, Ping, Lu, Feizhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964922/
https://www.ncbi.nlm.nih.gov/pubmed/29788960
http://dx.doi.org/10.1186/s12974-018-1183-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964922/
https://www.ncbi.nlm.nih.gov/pubmed/29788960
http://dx.doi.org/10.1186/s12974-018-1183-8

Ejemplares similares