Cargando…

Ecto-5′-nucleotidase (CD73) attenuates inflammation after spinal cord injury by promoting macrophages/microglia M2 polarization in mice

BACKGROUND: Immune activation, specifically activation of macrophages and resident microglia, leading to inflammation is a key component in the progression of spinal cord injury (SCI). Macrophages/microglia exist in two states—the classically activated M1 phenotype that confers pro-inflammatory effe...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xu, Shun, Zhu, Wei, Shao, Minghao, Zhang, Fan, Guo, Ji, Xu, Haocheng, Jiang, Jianyuan, Ma, Xiaosheng, Xia, Xinlei, Zhi, Xiuling, Zhou, Ping, Lu, Feizhou
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964922/ https://www.ncbi.nlm.nih.gov/pubmed/29788960 http://dx.doi.org/10.1186/s12974-018-1183-8

Ejemplares similares

Ecto-5'-nucleotidase (CD73) inhibits dorsal root ganglion neuronal apoptosis by promoting the Ado/cAMP/PKA/CREB pathway
por: Shao, Minghao, et al.
Publicado: (2021)

Physiological roles for ecto-5’-nucleotidase (CD73)
por: Colgan, Sean P., et al.
Publicado: (2006)

The Ecto-5′nucleotidase/CD73 Mediates Leishmania amazonensis Survival in Macrophages
por: Bajracharya, Bijay, et al.
Publicado: (2022)

CD73 alleviates GSDMD‐mediated microglia pyroptosis in spinal cord injury through PI3K/AKT/Foxo1 signaling
por: Xu, Shun, et al.
Publicado: (2020)

Ecto-5′-Nucleotidase (CD73) Regulates the Survival of CD8+ T Cells
por: Rosemblatt, Mariana V., et al.
Publicado: (2021)

Mesenchymal Stromal Cell Exosomes Mediate M2-like Macrophage Polarization through CD73/Ecto-5′-Nucleotidase Activity
por: Teo, Kristeen Ye Wen, et al.
Publicado: (2023)

Expression of ecto-5'-nucleotidase (CD73) in normal mammary gland and in breast carcinoma.
por: Krüger, K. H., et al.
Publicado: (1991)

Crucial Role for Ecto-5′-Nucleotidase (CD73) in Vascular Leakage during Hypoxia
por: Thompson, Linda F., et al.
Publicado: (2004)

Autoimmunity in CD73/Ecto-5′-Nucleotidase Deficient Mice Induces Renal Injury
por: Blume, Cornelia, et al.
Publicado: (2012)

High Expression of Ecto-Nucleotidases CD39 and CD73 in Human Endometrial Tumors
por: Aliagas, Elisabet, et al.
Publicado: (2014)

Identification of allosteric inhibitors of the ecto-5'-nucleotidase (CD73) targeting the dimer interface
por: Rahimova, Rahila, et al.
Publicado: (2018)

Exacerbation of Allergic Airway Inflammation in Mice Lacking ECTO-5′-Nucleotidase (CD73)
por: Caiazzo, Elisabetta, et al.
Publicado: (2020)

Infection of Human Macrophages by Leishmania infantum Is Influenced by Ecto-Nucleotidases
por: Peres, Nalu Teixeira de Aguiar, et al.
Publicado: (2018)

Ecto-5′-Nucleotidase (CD73) Regulates Host Inflammatory Responses and Exacerbates Murine Salmonellosis
por: Alam, M. Samiul, et al.
Publicado: (2014)

Unveiling the Role of Ecto-5′-Nucleotidase/CD73 in Astrocyte Migration by Using Pharmacological Tools
por: Adzic, Marija, et al.
Publicado: (2018)

Ecto-5’-nucleotidase: Structure function relationships
por: Sträter, Norbert
Publicado: (2006)

Differential Macrophage Activation Alters the Expression Profile of NTPDase and Ecto-5′-Nucleotidase
por: Zanin, Rafael Fernandes, et al.
Publicado: (2012)

Extracellular Adenosine Formation by Ecto-5’-Nucleotidase (CD73) Is No Essential Trigger for Early Phase Ischemic Preconditioning
por: Wolff, Georg, et al.
Publicado: (2015)

Ecto-5′-nucleotidase (CD73) is a biomarker for clear cell renal carcinoma stem-like cells
por: Song, Lei, et al.
Publicado: (2017)

The Volatile Anesthetic Isoflurane Increases Endothelial Adenosine Generation via Microparticle Ecto-5′-Nucleotidase (CD73) Release
por: Kim, Mihwa, et al.
Publicado: (2014)

The volatile anesthetic isoflurane induces ecto-5′-nucleotidase (CD73) to protect against renal ischemia and reperfusion injury
por: Kim, Mihwa, et al.
Publicado: (2013)

Mutual role of ecto-5'-nucleotidase/CD73 and concentrative nucleoside transporter 3 in the intestinal uptake of dAMP
por: Narumi, Katsuya, et al.
Publicado: (2019)

Novel microRNAs modulating ecto-5′-nucleotidase expression
por: Kordaß, Theresa, et al.
Publicado: (2023)

Evaluation of a Porous Bioabsorbable Interbody Mg-Zn Alloy Cage in a Goat Cervical Spine Model
por: Xu, Haocheng, et al.
Publicado: (2018)

Substrate binding modes of purine and pyrimidine nucleotides to human ecto-5′-nucleotidase (CD73) and inhibition by their bisphosphonic acid derivatives
por: Scaletti, Emma, et al.
Publicado: (2021)

Sequential hydrolysis of FAD by ecto-5′ nucleotidase CD73 and alkaline phosphatase is required for uptake of vitamin B(2) into cells
por: Shichinohe, Natsuki, et al.
Publicado: (2022)

TLR4 promotes microglial pyroptosis via lncRNA-F630028O10Rik by activating PI3K/AKT pathway after spinal cord injury
por: Xu, Shun, et al.
Publicado: (2020)

Ecto-5′-nucleotidase and intestinal ion secretion by enteropathogenic Escherichia coli
por: Crane, John K., et al.
Publicado: (2007)

Ecto-nucleotidases Activities in the Contents of Ovarian Endometriomas: Potential Biomarkers of Endometriosis
por: Texidó, Laura, et al.
Publicado: (2014)

Be Aware of Aggregators in the Search for Potential Human ecto-5′-Nucleotidase Inhibitors
por: Viviani, Lucas G., et al.
Publicado: (2018)

Identification and validation of ecto-5' nucleotidase as an immunotherapeutic target in multiple myeloma
por: Ray, Arghya, et al.
Publicado: (2022)

Recombinant ecto-5'-nucleotidase (CD73) has long lasting antinociceptive effects that are dependent on adenosine A(1 )receptor activation
por: Sowa, Nathaniel A, et al.
Publicado: (2010)

The Ecto-5’-Nucleotidase/CD73 Inhibitor, α,β-Methylene Adenosine 5’-Diphosphate, Exacerbates Carrageenan-Induced Pleurisy in Rat
por: Caiazzo, Elisabetta, et al.
Publicado: (2019)

Notch1 promotes resistance to cisplatin by up-regulating Ecto-5′-nucleotidase (CD73) in triple-negative breast cancer cells
por: Qi, Yuzhu, et al.
Publicado: (2023)

Deficits in Endogenous Adenosine Formation by Ecto-5′-Nucleotidase/CD73 Impair Neuromuscular Transmission and Immune Competence in Experimental Autoimmune Myasthenia Gravis
por: Oliveira, Laura, et al.
Publicado: (2015)

Alternative splicing of human NT5E in cirrhosis and hepatocellular carcinoma produces a negative regulator of ecto-5′-nucleotidase (CD73)
por: Snider, Natasha T., et al.
Publicado: (2014)

Effect of ecto-5′-nucleotidase (eN) in astrocytes on adenosine and inosine formation
por: Chu, Stephanie, et al.
Publicado: (2014)

Co-localization and confinement of ecto-nucleotidases modulate extracellular adenosine nucleotide distributions
por: Rahmaninejad, Hadi, et al.
Publicado: (2020)

Lack of Ecto-5′-Nucleotidase Protects Sensitized Mice against Allergen Challenge
por: Caiazzo, Elisabetta, et al.
Publicado: (2022)

Snake-Eyes Appearance on MRI Occurs during the Late Stage of Hirayama Disease and Indicates Poor Prognosis
por: Xu, Haocheng, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_rgonr0mq590hkesneq4ej4skmm