QSAR analysis of substituent effects on tambjamine anion transporters

The transmembrane anion transport activity of 43 synthetic molecules based on the structure of marine alkaloid tambjamine were assessed in model phospholipid (POPC) liposomes. The anionophoric activity of these molecules showed a parabolic dependence with lipophilicity, with an optimum range for tra...

Descripción completa

Detalles Bibliográficos
Autores principales: Knight, Nicola J., Hernando, Elsa, Haynes, Cally J. E., Busschaert, Nathalie, Clarke, Harriet J., Takimoto, Koji, García-Valverde, María, Frey, Jeremy G., Quesada, Roberto, Gale, Philip A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2016
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964965/
https://www.ncbi.nlm.nih.gov/pubmed/29899901
http://dx.doi.org/10.1039/c5sc03932k

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964965/
https://www.ncbi.nlm.nih.gov/pubmed/29899901
http://dx.doi.org/10.1039/c5sc03932k

Ejemplares similares