Biogenesis pathways of RNA guides in archaeal and bacterial CRISPR-Cas adaptive immunity

CRISPR-Cas is an RNA-mediated adaptive immune system that defends bacteria and archaea against mobile genetic elements. Short mature CRISPR RNAs (crRNAs) are key elements in the interference step of the immune pathway. A CRISPR array composed of a series of repeats interspaced by spacer sequences ac...

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Detalles Bibliográficos
Autores principales: Charpentier, Emmanuelle, Richter, Hagen, van der Oost, John, White, Malcolm F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5965381/
https://www.ncbi.nlm.nih.gov/pubmed/25994611
http://dx.doi.org/10.1093/femsre/fuv023

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5965381/
https://www.ncbi.nlm.nih.gov/pubmed/25994611
http://dx.doi.org/10.1093/femsre/fuv023

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