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Biogenesis pathways of RNA guides in archaeal and bacterial CRISPR-Cas adaptive immunity
CRISPR-Cas is an RNA-mediated adaptive immune system that defends bacteria and archaea against mobile genetic elements. Short mature CRISPR RNAs (crRNAs) are key elements in the interference step of the immune pathway. A CRISPR array composed of a series of repeats interspaced by spacer sequences ac...
Autores principales: | Charpentier, Emmanuelle, Richter, Hagen, van der Oost, John, White, Malcolm F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5965381/ https://www.ncbi.nlm.nih.gov/pubmed/25994611 http://dx.doi.org/10.1093/femsre/fuv023 |
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