Pathway choice between proteasomal and autophagic degradation

Efficient degradation of abnormal or aggregated proteins is crucial to protect the cell against proteotoxic stress. Selective targeting and disposal of such proteins usually occurs in a ubiquitin-dependent manner by proteasomes and macroautophagy/autophagy. Whereas proteasomes are efficient in degra...

Descripción completa

Detalles Bibliográficos
Autores principales: Lu, Kefeng, den Brave, Fabian, Jentsch, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Autophagic Punctum
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5965392/
https://www.ncbi.nlm.nih.gov/pubmed/28813181
http://dx.doi.org/10.1080/15548627.2017.1358851

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5965392/
https://www.ncbi.nlm.nih.gov/pubmed/28813181
http://dx.doi.org/10.1080/15548627.2017.1358851

Ejemplares similares